Bone age advancement in prepubertal children with obesity and premature adrenarche: possible potentiating factors. All statistical analyses were performed using the SPSS Precocious pubarche is associated with SGA, prematurity, weight gain, and obesity. The number of boys in this study was too small to detect any statistically significant differences in anthropometry or pubertal development. In one study, non-obese postmenarcheal adolescent girls with the history of PP had higher total body fat mass and more unfavorable fat distribution than those without a history of PP Children examined first at the mean age of 7. Results Results were analyzed separately for females and males.
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Open in a separate window. All biochemical samples had been drawn and analyzed at the baseline visit mean age of 7. J Steroid Biochem Mol Biol — Exaggerated adrenarche in a cohort of Scottish children: clinical features and biochemistry. First, excess androgen exposure in PA could lead to increased peripheral conversion of weak adrenal androgens to more potent androgens and estrogens.